The pharmaceutical industry is one of the most critical sectors globally, requiring stringent control over the storage and transportation of products to ensure efficacy and safety. The integration of the Internet of Things (IoT) into pharmaceutical logistics offers unprecedented opportunities for optimization, real-time monitoring, and enhanced decision-making. This article explores the application of IoT in pharmaceutical logistics, focusing on its potential to improve supply chain efficiency, ensure regulatory compliance, and reduce costs. The study employs a mixed-methods approach, combining literature review, case studies, and data analysis to evaluate the impact of IoT on pharmaceutical logistics. The results demonstrate significant improvements in temperature control, inventory management, and delivery times. The discussion highlights the challenges and opportunities associated with IoT adoption, while the conclusion provides recommendations for future research and implementation.