3D printing, also known as additive manufacturing, has emerged as a transformative technology in various industries, including pharmaceuticals. This review explores the application of 3D printing in on-demand drug manufacturing, focusing on its potential to revolutionize personalized medicine, improve drug delivery systems, and enhance the efficiency of pharmaceutical production. The article delves into the materials and methods used in 3D printing for drug manufacturing, presents recent advancements, and discusses the challenges and future prospects of this technology. The review concludes that 3D printing holds significant promise for the future of drug manufacturing, particularly in the context of personalized medicine and on-demand production.