A simple, accurate, precise, and cost-effective UV spectrophotometric method has been developed and validated for the estimation of paracetamol in bulk drug and tablet dosage forms. The method was developed based on the measurement of absorbance at 243 nm in 0.1 M sodium hydroxide solution. The method showed excellent linearity in the concentration range of 2-12 μg/mL with a correlation coefficient of 0.9998. The method was validated according to ICH Q2(R1) guidelines for various parameters including accuracy, precision, linearity, range, specificity, limit of detection (LOD), limit of quantification (LOQ), and robustness. The percentage recovery was found to be 99.85-100.15%, indicating good accuracy of the method. The relative standard deviation for repeatability and intermediate precision was less than 2%, demonstrating excellent precision. The developed method was successfully applied for the estimation of paracetamol in commercial tablet formulations with satisfactory results. The method is suitable for routine quality control analysis in pharmaceutical industries and can be used for the determination of paracetamol in bulk drug and tablet dosage forms.